At least 3,478 Palestinians killed by Israel as aid remains stuck on border.

GAZA -- Egypt agreed to reopen its border crossing with the Gaza Strip to allow aid to reach Palestinians, the US said, as the humanitarian crisis worsened for the 2.3 million people trapped in the enclave and anti-Israel protests flared across the Middle East.

The region remained volatile in the aftermath of an Israeli air strike at Gaza's Al-Ahli al-Arabi hospital late on Tuesday, which Palestinian officials said killed 471 people.

The Gaza health ministry said 3,478 Palestinians have been killed and 12,065 injured in Israeli air strikes on the besieged enclave since Oct 7.

Demonstrations erupted in the Israeli-occupied Palestinian West Bank, Iran, Jordan, Lebanon, Tunisia and elsewhere amid outrage across the Middle East over the hospital attack. Lebanese security forces fired tear gas and water cannons at protesters throwing projectiles near the US embassy in Beirut, TV footage showed.

Israeli forces shot dead two Palestinian teenagers in the West Bank during protests, Palestinian officials said, while Palestinian official news agency WAFA said Israeli forces killed a Palestinian man during a raid on the West Bank village of Budrus.

US President Joe Biden discussed aid for Gaza with Egyptian President Abdel Fattah El-Sisi by phone late on...