Gene that naturally protects people against Covid discovered.
ISLAMABAD -- A team of Brazilian researchers has discovered that a gene can protect people, even those aged 90 and above, from the deadly Covid disease.
Two research papers found that the frequency of variants of the gene 'MUC22' was twice as high in the mild Covid-19 group as in severe patients, and higher still in resilient super-agers.
This gene belongs to the "mucin" family and is associated with the production of mucus, which lubricates and protects the airways.
On the other hand, overproduction of mucus has been linked to the lung inflammation typical of severe Covid-19.
One research paper involved a group of resilient older people aged 90 or more, and the other analyzed a case of severe Covid-19 in identical twins, only one of whom suffered from long-term symptoms of the disease.
"If we can really prove that some genes promote resistance to SARS-CoV-2, the same may also be true for other viruses. More research can then be based on these findings to try to understand the mechanisms underlying this resilience and develop medications that enhance protection against viral infections," said Mayana Zatz, professor of Human and Medical Genetics at the University of Sao Paulo and lead author of the articles published in the journal Frontiers in Immunology.
In one study, the researchers analyzed data sets for a cohort of 87 "resilient super-agers" a" patients over 90 who recovered from mild Covid-19 or...
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